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Protein
Submitted name:

Solute carrier family 44, member 1, isoform CRA_a

Gene

SLC44A1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Solute carrier family 44, member 1, isoform CRA_aImported
Gene namesi
Name:SLC44A1Imported
ORF Names:hCG_29051Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000070214.15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei29 – 51HelicalSequence analysisAdd BLAST23
Transmembranei214 – 233HelicalSequence analysisAdd BLAST20
Transmembranei239 – 263HelicalSequence analysisAdd BLAST25
Transmembranei289 – 308HelicalSequence analysisAdd BLAST20
Transmembranei314 – 335HelicalSequence analysisAdd BLAST22
Transmembranei342 – 363HelicalSequence analysisAdd BLAST22
Transmembranei383 – 416HelicalSequence analysisAdd BLAST34
Transmembranei538 – 559HelicalSequence analysisAdd BLAST22
Transmembranei565 – 587HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiA0A024R151

Expressioni

Gene expression databases

BgeeiENSG00000070214
ExpressionAtlasiA0A024R151 baseline and differential

Family & Domainsi

Sequence similaritiesi

Belongs to the CTL (choline transporter-like) family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1362 Eukaryota
ENOG410XS0P LUCA
KOiK06515
OMAiVYWIMTL
OrthoDBiEOG091G0CMQ

Family and domain databases

InterProiView protein in InterPro
IPR007603 Choline_transptr-like
PANTHERiPTHR12385 PTHR12385, 1 hit
PfamiView protein in Pfam
PF04515 Choline_transpo, 1 hit

Sequencei

Sequence statusi: Complete.

A0A024R151-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGCCSSASSA AQSSKREWKP LEDRSCTDIP WLLLFILFCI GMGFICGFSI
60 70 80 90 100
ATGAAARLVS GYDSYGNICG QKNTKLEAIP NSGMDHTQRK YVFFLDPCNL
110 120 130 140 150
DLINRKIKSV ALCVAACPRQ ELKTLSDVQK FAEINGSALC SYNLKPSEYT
160 170 180 190 200
TSPKSSVLCP KLPVPASAPI PFFHRCAPVN ISCYAKFAEA LITFVSDNSV
210 220 230 240 250
LHRLISGVMT SKEIILGLCL LSLVLSMILM VIIRYISRVL VWILTILVIL
260 270 280 290 300
GSLGGTGVLW WLYAKQRRSP KETVTPEQLQ IAEDNLRALL IYAISATVFT
310 320 330 340 350
VILFLIMLVM RKRVALTIAL FHVAGKVFIH LPLLVFQPFW TFFALVLFWV
360 370 380 390 400
YWIMTLLFLG TTGSPVQNEQ GFVEFKISGP LQYMWWYHVV GLIWISEFIL
410 420 430 440 450
ACQQMTVAGA VVTYYFTRDK RNLPFTPILA SVNRLIRYHL GTVAKGSFII
460 470 480 490 500
TLVKIPRMIL MYIHSQLKGK ENACARCVLK SCICCLWCLE KCLNYLNQNA
510 520 530 540 550
YTATAINSTN FCTSAKDAFV ILVENALRVA TINTVGDFML FLGKVLIVCS
560 570 580 590 600
TGLAGIMLLN YQQDYTVWVL PLIIVCLFAF LVAHCFLSIY EMVVDVLFLC
610 620 630 640 650
FAIDTKYNDG SPGREFYMDK VLMEFVENSR KAMKEAGKGG VADSRELKPM

ASGASSA
Length:657
Mass (Da):73,302
Last modified:July 9, 2014 - v1
Checksum:i10D70CAB8E33E3AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471105 Genomic DNA Translation: EAW58995.1
CH471105 Genomic DNA Translation: EAW58996.1
RefSeqiNP_536856.2, NM_080546.4
UniGeneiHs.573495

Genome annotation databases

GeneIDi23446
KEGGihsa:23446

Similar proteinsi

Entry informationi

Entry nameiA0A024R151_HUMAN
AccessioniPrimary (citable) accession number: A0A024R151
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: May 23, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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