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Protein
Submitted name:

p21(CDKN1A)-activated kinase 4, isoform CRA_a

Gene

PAK4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotationImported, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
p21(CDKN1A)-activated kinase 4, isoform CRA_aImported
Gene namesi
Name:PAK4Imported
ORF Names:hCG_20282Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Expressioni

Gene expression databases

BgeeiENSG00000130669.
ExpressionAtlasiA0A024R0J1. baseline and differential.

Structurei

3D structure databases

SMRiA0A024R0J1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 24CRIBInterPro annotationAdd BLAST14
Domaini321 – 572Protein kinaseInterPro annotationAdd BLAST252

Phylogenomic databases

eggNOGiKOG0578. Eukaryota.
ENOG410XP4K. LUCA.
KOiK05734.
OMAiRQENGMP.
OrthoDBiEOG091G0OT5.

Family and domain databases

CDDicd01093. CRIB_PAK_like. 1 hit.
Gene3Di3.90.810.10. 1 hit.
InterProiView protein in InterPro
IPR000095. CRIB_dom.
IPR011009. Kinase-like_dom.
IPR033923. PAK_BD.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
PfamiView protein in Pfam
PF00786. PBD. 1 hit.
PF00069. Pkinase. 1 hit.
SMARTiView protein in SMART
SM00285. PBD. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS50108. CRIB. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A024R0J1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFGKRKKRVE ISAPSNFEHR VHTGFDQHEQ KFTGLPRQWQ SLIEESARRP
60 70 80 90 100
KPLVDPACIT SIQPGAPKTI VRGSKGAKDG ALTLLLDEFE NMSVTRSNSL
110 120 130 140 150
RRDSPPPPAR ARQENGMPEE PATTARGGPG KAGSRGRFAG HSEAGGGSGD
160 170 180 190 200
RRRAGPEKRP KSSREGSGGP QESSRDKRPL SGPDVGTPQP AGLASGAKLA
210 220 230 240 250
AGRPFNTYPR ADTDHPSRGA QGEPHDVAPN GPSAGGLAIP QSSSSSSRPP
260 270 280 290 300
TRARGAPSPG VLGPHASEPQ LAPPACTPAA PAVPGPPGPR SPQREPQRVS
310 320 330 340 350
HEQFRAALQL VVDPGDPRSY LDNFIKIGEG STGIVCIATV RSSGKLVAVK
360 370 380 390 400
KMDLRKQQRR ELLFNEVVIM RDYQHENVVE MYNSYLVGDE LWVVMEFLEG
410 420 430 440 450
GALTDIVTHT RMNEEQIAAV CLAVLQALSV LHAQGVIHRD IKSDSILLTH
460 470 480 490 500
DGRVKLSDFG FCAQVSKEVP RRKSLVGTPY WMAPELISRL PYGPEVDIWS
510 520 530 540 550
LGIMVIEMVD GEPPYFNEPP LKAMKMIRDN LPPRLKNLHK VSPSLKGFLD
560 570 580 590
RLLVRDPAQR ATAAELLKHP FLAKAGPPAS IVPLMRQNRT R
Length:591
Mass (Da):64,072
Last modified:July 9, 2014 - v1
Checksum:i04C2A5C0B06427D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471126 Genomic DNA. Translation: EAW56858.1.
CH471126 Genomic DNA. Translation: EAW56859.1.
CH471126 Genomic DNA. Translation: EAW56864.1.
CH471126 Genomic DNA. Translation: EAW56866.1.
RefSeqiNP_001014831.1. NM_001014831.2.
NP_001014832.1. NM_001014832.1.
NP_005875.1. NM_005884.3.
XP_011524618.1. XM_011526316.1.
XP_011524619.1. XM_011526317.2.
XP_011524620.1. XM_011526318.2.
XP_011524621.1. XM_011526319.2.
UniGeneiHs.20447.

Genome annotation databases

GeneIDi10298.
KEGGihsa:10298.

Similar proteinsi

Entry informationi

Entry nameiA0A024R0J1_HUMAN
AccessioniPrimary (citable) accession number: A0A024R0J1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: August 30, 2017
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.