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Protein
Submitted name:

Phosphatidic acid phosphatase type 2A, isoform CRA_b

Gene

PPAP2A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Phosphatidic acid phosphatase type 2A, isoform CRA_bImported
Gene namesi
Name:PPAP2AImported
ORF Names:hCG_39580Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000067113.16.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 27HelicalSequence analysisAdd BLAST21
Transmembranei59 – 82HelicalSequence analysisAdd BLAST24
Transmembranei94 – 112HelicalSequence analysisAdd BLAST19
Transmembranei166 – 186HelicalSequence analysisAdd BLAST21
Transmembranei229 – 251HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiA0A024QZU7.
PRIDEiA0A024QZU7.

Expressioni

Gene expression databases

BgeeiENSG00000067113.
ExpressionAtlasiA0A024QZU7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliA0A024QZU7.
SMRiA0A024QZU7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini103 – 244acidPPcInterPro annotationAdd BLAST142

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3030. Eukaryota.
COG0671. LUCA.
OMAiGNHYRNS.
OrthoDBiEOG091G0K5H.
PhylomeDBiA0A024QZU7.

Family and domain databases

InterProiView protein in InterPro
IPR028670. LPP1.
IPR036938. P_Acid_Pase_2/haloperoxi_sf.
IPR000326. P_Acid_Pase_2/haloperoxidase.
PANTHERiPTHR10165:SF26. PTHR10165:SF26. 1 hit.
PfamiView protein in Pfam
PF01569. PAP2. 1 hit.
SMARTiView protein in SMART
SM00014. acidPPc. 1 hit.
SUPFAMiSSF48317. SSF48317. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A024QZU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFDKTRLPYV ALDVLCVLLA SMPMAVLKLG QIYPFQRGFF CKDNSINYPY
60 70 80 90 100
HDSTVTSTVL ILVGVGLPIS SIILGETLSV YCNLLHSNSF IRNNYIATIY
110 120 130 140 150
KAIGTFLFGA AASQSLTDIA KYSIGRLRPH FLDVCDPDWS KINCSDGYIE
160 170 180 190 200
YYICRGNAER VKEGRLSFYS GHSSFSMYCM LFVALYLQAR MKGDWARLLR
210 220 230 240 250
PTLQFGLVAV SIYVGLSRVS DYKHHWSDVL TGLIQGALVA ILVAVYVSDF
260 270 280
FKERTSFKER KEEDSHTTLH ETPTTGNHYP SNHQP
Length:285
Mass (Da):32,150
Last modified:July 9, 2014 - v1
Checksum:i7209608A420380CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471123 Genomic DNA. Translation: EAW54923.1.
RefSeqiNP_795714.1. NM_176895.2.
UniGeneiHs.696231.

Genome annotation databases

GeneIDi8611.

Similar proteinsi

Entry informationi

Entry nameiA0A024QZU7_HUMAN
AccessioniPrimary (citable) accession number: A0A024QZU7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 9, 2014
Last sequence update: July 9, 2014
Last modified: October 25, 2017
This is version 25 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.