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Protein

Ribonuclease 3

Gene

rnc

Organism
Bacteroides fragilis str. Korea 419
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi62MagnesiumUniRule annotation1
Active sitei66UniRule annotation1
Metal bindingi131MagnesiumUniRule annotation1
Active sitei134UniRule annotation1
Metal bindingi134MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease, RNA-binding, rRNA-bindingUniRule annotationSAAS annotation
Biological processmRNA processingUniRule annotationSAAS annotation, rRNA processingUniRule annotationSAAS annotation, tRNA processingUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease 3UniRule annotation (EC:3.1.26.3UniRule annotation)
Alternative name(s):
Ribonuclease IIIUniRule annotation
Short name:
RNase IIIUniRule annotation
Gene namesi
Name:rncUniRule annotation
ORF Names:M065_0245Imported, M065_0352Imported, M065_0708Imported, M065_0917Imported, M065_1263Imported, M065_5312Imported, M065_5451Imported, M065_6033Imported
OrganismiBacteroides fragilis str. Korea 419Imported
Taxonomic identifieri1339269 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
Proteomesi
  • UP000021843 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotationSAAS annotation

Structurei

3D structure databases

SMRiA0A016ENS4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 145RNase IIIInterPro annotationAdd BLAST126
Domaini173 – 242DRBMInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the ribonuclease III family.SAAS annotation

Family and domain databases

CDDicd00593. RIBOc. 1 hit.
Gene3Di1.10.1520.10. 1 hit.
HAMAPiMF_00104. RNase_III. 1 hit.
InterProiView protein in InterPro
IPR014720. dsRBD_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
IPR036389. RNase_III_sf.
PfamiView protein in Pfam
PF00035. dsrm. 1 hit.
PF14622. Ribonucleas_3_3. 1 hit.
SMARTiView protein in SMART
SM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
SUPFAMiSSF69065. SSF69065. 1 hit.
TIGRFAMsiTIGR02191. RNaseIII. 1 hit.
PROSITEiView protein in PROSITE
PS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A0A016ENS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRNKIDKIR LLFRKDRESY SCFYRILGFY PRNIRLYEQA LLHKSTAVRS
60 70 80 90 100
EKGRPLNNER LEFLGDAILD AIVGDIVYQH FEGKREGFLT NTRSKIVQRE
110 120 130 140 150
TLNKLAVEIG LDKLIKYSTR SSSHNSYMYG NAFEAFIGAI YLDRGYECCK
160 170 180 190 200
QFMERRIIEP YIDLDKLSRK EVNFKSKLIE WSQKNKMEVS FELIEQSLDK
210 220 230 240 250
ENNPVFQTEV RIEGILGGSG TGYSKKESQQ NAAQMTLKKI KGDPEFMASV
260 270 280 290
QEAKTQNNVP AEDTTPESET SLTAENQQID EIISTEEISV
Length:290
Mass (Da):33,486
Last modified:June 11, 2014 - v1
Checksum:iC3A7E6AD5E9B0275
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JGDW01000227 Genomic DNA. Translation: EXZ91449.1.
JGDW01000159 Genomic DNA. Translation: EXZ92185.1.
JGDW01000142 Genomic DNA. Translation: EXZ92296.1.
JGDW01000022 Genomic DNA. Translation: EXZ96392.1.
JGDW01000021 Genomic DNA. Translation: EXZ96497.1.
JGDW01000019 Genomic DNA. Translation: EXZ96755.1.
JGDW01000018 Genomic DNA. Translation: EXZ96927.1.
JGDW01000017 Genomic DNA. Translation: EXZ97344.1.

Genome annotation databases

EnsemblBacteriaiEXZ91449; EXZ91449; M065_6033.
EXZ92185; EXZ92185; M065_5451.
EXZ92296; EXZ92296; M065_5312.
EXZ96392; EXZ96392; M065_1263.
EXZ96497; EXZ96497; M065_0917.
EXZ96755; EXZ96755; M065_0708.
EXZ96927; EXZ96927; M065_0352.
EXZ97344; EXZ97344; M065_0245.
PATRICifig|1339269.3.peg.1244.

Similar proteinsi

Entry informationi

Entry nameiA0A016ENS4_BACFG
AccessioniPrimary (citable) accession number: A0A016ENS4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: March 28, 2018
This is version 32 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported