<p>An evidence describes the source of an annotation, e.g. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc.</p>
<p><a href="/manual/evidences">More…</a></p>
Function
<p>Position-independent general annotations used to be found in the 'General annotation (Comments)' section in the previous version of the UniProtKB entry view. They provide any useful information about the protein, mostly biological knowledge. General annotations are frequently written in free text, although we increasingly try to standardize them and use controlled vocabulary wherever possible. The flat file and XML formats still group all general annotation together in a "Comments section" (CC, <comment>). <p><a href='/help/general_annotation' target='_top'>More...</a></p>[CC]i
Miscellaneous
<p>Position-independent general annotations used to be found in the 'General annotation (Comments)' section in the previous version of the UniProtKB entry view. They provide any useful information about the protein, mostly biological knowledge. General annotations are frequently written in free text, although we increasingly try to standardize them and use controlled vocabulary wherever possible. The flat file and XML formats still group all general annotation together in a "Comments section" (CC, <comment>). <p><a href='/help/general_annotation' target='_top'>More...</a></p>[CC]i
Subunit structure
<p>Position-independent general annotations used to be found in the 'General annotation (Comments)' section in the previous version of the UniProtKB entry view. They provide any useful information about the protein, mostly biological knowledge. General annotations are frequently written in free text, although we increasingly try to standardize them and use controlled vocabulary wherever possible. The flat file and XML formats still group all general annotation together in a "Comments section" (CC, <comment>). <p><a href='/help/general_annotation' target='_top'>More...</a></p>[CC]i
Subcellular location
<p>Position-independent general annotations used to be found in the 'General annotation (Comments)' section in the previous version of the UniProtKB entry view. They provide any useful information about the protein, mostly biological knowledge. General annotations are frequently written in free text, although we increasingly try to standardize them and use controlled vocabulary wherever possible. The flat file and XML formats still group all general annotation together in a "Comments section" (CC, <comment>). <p><a href='/help/general_annotation' target='_top'>More...</a></p>[CC]i
Domain
<p>Position-independent general annotations used to be found in the 'General annotation (Comments)' section in the previous version of the UniProtKB entry view. They provide any useful information about the protein, mostly biological knowledge. General annotations are frequently written in free text, although we increasingly try to standardize them and use controlled vocabulary wherever possible. The flat file and XML formats still group all general annotation together in a "Comments section" (CC, <comment>). <p><a href='/help/general_annotation' target='_top'>More...</a></p>[CC]i
Domain
<p>Sequence annotations describe regions or sites of interest in the protein sequence, such as post-translational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. Sequence conflicts between references are also described in this manner.<p><a href='/help/sequence_annotation' target='_top'>More...</a></p>[FT]i
Reviewed (Swiss-Prot) - Manually annotated Records with information extracted from literature and curator-evaluated computational analysis.
Unreviewed (TrEMBL) - Computationally analyzed Records that await full manual annotation.
The UniProt Knowledgebase (UniProtKB) is the central hub for the collection of functional information on proteins, with accurate, consistent and rich annotation. In addition to capturing the
core data mandatory for each UniProtKB entry (mainly, the amino acid sequence, protein name or description, taxonomic data and citation information), as much annotation information as possible is added.
<p>The ‘Share’ button allows you to share a custom <span class="caps">URL</span> including the columns in your result view.</p>
<p><a href="/help/programmatic_access#retrieving_entries_via_queries">More…</a></p>
