Ajellomyces capsulate (syn. Histoplasma capsulatum) is the causal agent of Histoplasmosis, also known as Darling's disease. Found throughout the world commonly in bat and bird droppings, the disease is contracted by breathing in the fungal spores. Most people do not display any symptoms and are unaware they are infected, but in immunocompromised individuals the disease can spread from the lungs to other organs of the body and can be fatal if left untreated.

Ajellomyces capsulatus strain H88 has been sequenced by The Broad Institute at 7.8X coverage using whole genome shotgun sequencing. There are currently 16 multi-component and singleton scaffolds for the chromosomal contigs and 1 scaffold for the mitochondrial contig.