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Overview

Proteome nameMycobacterium abscessus - Reference proteome
Proteins4,940
Proteome IDiUP000007137
StrainATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543
Taxonomy561007 - Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)
Last modifiedFebruary 4, 2017
Genome assembly and annotationi GCA_000069185.1 from ENA/EMBL
Pan proteomei This proteome is part of the Mycobacterium abscessus pan proteome (fasta)

Mycobacterium abscessus is a rapidly growing, non-tuberculous mycobacteria which is pathogenic for humans. It is commonly associated with contaminated traumatic skin wounds and with post-surgical soft tissue infections, in addition to being one of the mycobacteria most often isolated from cystic fibrosis patients. It is very resistant to common antimicrobial agents, which makes it difficult to treat. It is ubiquitously present in natural waters, decaying vegetation, sewage water, as well as in drinking water tanks and municipal tap water. Nosocomial outbreaks/pseudooutbreaks of M. abscessus have been described in connection with automated endoscope washers and in hospital water supplies. This strain, also known as CIP 104536, is the type strain and the first rapid-growth pathogenic mycobacterium to be sequenced, and will give important comparative information (adapted from PubMed 16725007).

Mycobacteria have an unusual outer membrane approximately 8nm thick, despite being considered Gram-positive. The outer membrane and the mycolic acid-arabinoglactan-peptidoglycan polymer form the cell wall, which constitutes an efficient permeability barrier in conjunction with the cell inner membrane.

Componentsi

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Component nameGenome Accession(s)
Proteins
Chromosome4918
Plasmid pMAB22

Publications

  1. "Non mycobacterial virulence genes in the genome of the emerging pathogen Mycobacterium abscessus."
    Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M., Macheras E., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L., Gaillard J.L.
    PLoS ONE 2009:E5660-E5660(2009) [PubMed] [Europe PMC] [Abstract]