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Overview

Proteome nameAnopheles gambiae African malaria mosquito - Reference proteome
Proteins13,373
Proteome IDiUP000007062
StrainPEST
Taxonomy7165 - Anopheles gambiae
Last modifiedMarch 18, 2017
Genome assembly GCA_000005575.1 from ENA/EMBL
© upload.wikimedia.org

Anopheles gambiae is the primary mosquito vector responsible for the transmission of malaria (Plasmodium falciparum) in most of sub-Saharan Africa; and is also considered to be one of the most efficient vectors of malaria. It feeds almost exclusively on humans, late at night, indoors as well as outdoors. Anopholes gambiae can show more opportunistic feeding behaviors depending on location, host availability and the genetic make-up of the mosquito population. The larvae develop in temporary bodies of fresh water and the adults rest primarily indoors, but resting outdoors has also been observed.

The Anopheles gambiae complete genome sequence of the strain PEST was published in 2002. It contains about 280 Mb, and approximately 12,800 protein-coding genes. The high degree of genetic variation observed in the strain PEST is probably the result of recombination among the different cytotypes that contributed to the PEST strain, resulting in a mosaic genome.

Componentsi

DownloadView all proteins
Component nameGenome Accession(s)
Proteins
Chromosome 2L3176
Chromosome 2R4098
Chromosome 3L1963
Chromosome 3R2522
Chromosome X1170
Mitochondrion13
Unplaced
0
Unassembled WGS sequence689

Publications

  1. "The mitochondrial genome of the mosquito Anopheles gambiae: DNA sequence, genome organization, and comparisons with mitochondrial sequences of other insects."
    Beard C.B., Hamm D.M., Collins F.H.
    Insect Mol. Biol. 1993:103-124(1993) [PubMed] [Europe PMC] [Abstract]
  2. "The genome sequence of the malaria mosquito Anopheles gambiae."
    Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F.
    , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.
    Science 2002:129-149(2002) [PubMed] [Europe PMC] [Abstract]