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Proteome nameAnopheles gambiae African malaria mosquito - Reference proteome
Proteome IDiUP000007062
Taxonomy7165 - Anopheles gambiae
Last modifiedJanuary 5, 2018
Genome assembly and annotationi GCA_000005575.1 from ENA/EMBL

Anopheles gambiae is the primary mosquito vector responsible for the transmission of malaria (Plasmodium falciparum) in most of sub-Saharan Africa; and is also considered to be one of the most efficient vectors of malaria. It feeds almost exclusively on humans, late at night, indoors as well as outdoors. Anopholes gambiae can show more opportunistic feeding behaviors depending on location, host availability and the genetic make-up of the mosquito population. The larvae develop in temporary bodies of fresh water and the adults rest primarily indoors, but resting outdoors has also been observed.

The Anopheles gambiae complete genome sequence of the strain PEST was published in 2002. It contains about 280 Mb, and approximately 12,800 protein-coding genes. The high degree of genetic variation observed in the strain PEST is probably the result of recombination among the different cytotypes that contributed to the PEST strain, resulting in a mosaic genome.


DownloadView all proteins
Component nameGenome Accession(s)
Chromosome 2L3187
Chromosome 2R4110
Chromosome 3L2032
Chromosome 3R2540
Chromosome X1176
Unassembled WGS sequence688


  1. "The genome sequence of the malaria mosquito Anopheles gambiae."
    Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F.
    , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.
    Science 2002:129-149(2002) [PubMed] [Europe PMC] [Abstract]
  2. "The mitochondrial genome of the mosquito Anopheles gambiae: DNA sequence, genome organization, and comparisons with mitochondrial sequences of other insects."
    Beard C.B., Hamm D.M., Collins F.H.
    Insect Mol. Biol. 1993:103-124(1993) [PubMed] [Europe PMC] [Abstract]