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Overview

StatusReference proteome
Proteins29,966
Proteome IDiUP000002494
Taxonomy10116 - Rattus norvegicus
StrainBrown Norway
Last modifiedApril 2, 2018
Genome assembly and annotationi GCA_000001895.4 from Ensembl
© www.nenature.com

Rattus norvegicus (also called the brown rat, Hanover rat, Norwegian rat, Brown Norway rat) is a common rodent closely related to mouse. The species originated in Asia, not Norway as the name suggests, and has spread throughout the world.

The rat is a major pest and a reservoir of pathogens, being involved in the transmission of infectious diseases such as cholera, bubonic plague and typhus. On the other hand, Rattus norvegicus was the first mammalian species to be domesticated for scientific research.

The rat is an indispensable model organism in biomedical research, especially in cardiovascular and psychological research, and in therapeutic efficacy and toxicity studies. It is the third mammalian species to have its genome sequenced.

The reference proteome of Rattus norvegicus is derived from the genome sequence of strain Brown Norway (BN) that was published in 2004. The sequence data were mostly from two inbred female animals of strain BN/SsNHsd/Mcwi. The assembled genome size is 2.75 Gb.

Componentsi

DownloadView all proteins
Component nameGenome Accession(s)
Proteins
Unplaced
3115
Mitochondrion13
Chromosome 13563
Chromosome 21768
Chromosome 32124
Chromosome 41659
Chromosome 51601
Chromosome 61135
Chromosome 71636
Chromosome 81490
Chromosome 91075
Chromosome 102101
Chromosome 11718
Chromosome 12823
Chromosome 13841
Chromosome 14848
Chromosome 15862
Chromosome 16770
Chromosome 17759
Chromosome 18640
Chromosome 19668
Chromosome 20865
Chromosome X1026
Chromosome Y12

Publications

  1. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
    Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
    , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
    Nature 2004:493-521(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The Mitochondrial Genome of Rattus Norvegicus strain Brown Norway."
    McLeod M.P., Muzny D.M., Metzker M.L., Abramzon S., Adams C., Alder J., Allen C., Allen H., Alsbrooks S., Amin A., Anguiano D., Anyalebechi V., Aoyagi A., Ayodeji M., Baca E., Baden H., Baldwin D., Bandaranaike D.
    , Barber M., Barnstead M., Benahmed F., Biswalo K., Blair J., Blankenburg K., Blyth P., Brown M., Bryant N., Buhay C., Burch P., Burrell K., Calderon E., Cardenas V., Carter K., Cavazos I., Ceasar H., Center A., Chacko J., Chavez D., Chen G., Chen R., Chen Y., Chen Z., Chu J., Cleveland C., Cockrell R., Cox C., Coyle M., Cree A., D'Souza L., Davila M.L., Davis C., Davy-Carroll L., De Anda C., Dederich D., Delgado O., Denson S., Deramo C., Ding Y., Dinh H., Divya K., Draper H., Dugan-Rocha S., Dunn A., Durbin K., Duval B., Eaves K., Egan A., Escotto M., Eugene C., Evans C.A., Falls T., Fan G., Fernandez S., Finley M., Flagg N., Forbes L., Foster M., Foster P., Fraser C.M., Gabisi A., Ganta R., Garcia A., Garner T., Garza M., Gebregeorgis E., Geer K., Gill R., Grady M., Guerra W., Guevara W., Gunaratne P., Haaland W., Hamil C., Hamilton C., Hamilton K., Harvey Y., Havlak P., Hawes A., Henderson N., Hernandez J., Hernandez R., Hines S., Hladun S.L., Hodgson A., Hogues M., Hollins B., Howells S., Hulyk S., Hume J., Idlebird D., Jackson A., Jackson L., Jacob L., Jiang H., Johnson B., Johnson R., Jolivet A., Karpathy S., Kelly S., Kelly S., Khan Z., King L., Kovar C., Kowis C., Kraft C.L., Lebow H., Levan J., Lewis L., Li Z., Liu J., Liu J., Liu W., Liu Y., London P., Longacre S., Lopez J., Lorensuhewa L., Loulseged H., Lozado R.J., Lu X., Ma J., Maheshwari M., Mahindartne M., Mahmoud M., Malloy K., Mangum A., Mangum B., Mapua P., Martin K., Martin R., Martinez E., Mawhiney S., McNeill T.Z., Meenen E., Milosavljevic A., Miner G., Minja E., Montemayor J., Moore S., Morgan M., Morris K., Morris S., Munidasa M., Murphy M., Nair L., Nankervis C., Neal D., Newton N., Nguyen N., Norris S., Nwaokelemeh O., Okwuonu G., Olarnpunsagoon A., Pal S., Parks K., Pasternak S., Paul H., Perez A., Perez L., Pfannkoch C., Plopper F., Poindexter A., Popovic D., Primus E., Pu L.-L., Puazo M., Quiroz J., Rachlin E., Reeves K., Regier M.A., Reigh R., Reilly B., Reilly M., Ren Y., Reuter M., Richards S., Riggs F., Rives C., Rodkey T., Rojas A., Rose M., Rose R., Ruiz S.J., Sanders W., Savery G., Scherer S., Scott G., Shatsman S., Shen H., Shetty J., Shvartsbeyn A., Sisson I., Sitter C.D., Smajs D., Sneed A., Sodergren E., Song X.-Z., Sorelle R., Sosa J., Steimle M., Strong R., Sutton A., Svatek A., Tabor P., Taylor C., Taylor T., Thomas N., Thomas S., Tingey A., Trejos Z., Usmani K., Valas R., Vera V., Villasana D., Waldron L., Walker B., Wang J., Wang Q., Wang S., Warren J., Warren R., Wei X., White F., Williams G., Willson R., Wleczyk R., Wooden H., Worley K., Wright D., Wright R., Wu J., Yakub S., Yen J., Yoon L., Yoon V., Yu F., Zhang J., Zhou J., Zhou X., Zhao S., Dunn D., von Niederhausern A., Weiss R., Smith D.R., Holt R.A., Smith H.O., Weinstock G., Gibbs R.A.
    Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases
  3. Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases

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