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StatusReference proteome
Proteome IDiUP000002145
Taxonomy203119 - Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372)
StrainATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372
Last modifiedJanuary 23, 2018
Genome assembly and annotationi GCA_000015865.1 from ENA/EMBL

Clostridium thermocellum is a Gram-positive, anaerobic, thermophilic plant cell wall degrading bacterium capable of converting cellulosic substrates into ethanol. Degradation of cellulose occurs extracellularly in a large complex called the cellulosome. This nanomachine contains about 20 catalytic components, and can attach to the surface of the host organism. The complex is built on a "scaffoldin" subunit onto which the catalytic subunits are added through interactions of the "cohesion" domains of the enzymes with the "dockerin" domains on the scaffold. The C.thermocellum cellulosome is the best-characterized cellulase complex and thus serves as a paradigm. Continuing research on the cellulosome and its producer will provide crucial information for better understanding the cellulolytic reaction, a key process in biomass conversion (adapted from


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