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StatusReference proteome
Proteome IDiUP000000811
Taxonomy243276 - Treponema pallidum (strain Nichols)
Last modifiedJanuary 24, 2018
Genome assembly and annotationi GCA_000008605.1 from ENA/EMBL
Pan proteomei This proteome is part of the Treponema pallidum Nichols pan proteome (fasta)

Treponema pallidum, is a helical to sinusoidal spirochaete with 2 membranes, a thin peptidoglycan layer and flagella that lie in the periplasmic space. It is the causative agent of syphilis, plays a role in the transmission and acquisition of HIV, and is a major cause of stillbirth and perinatal morbidity in the developing world. Even if the primary infection is localized, bacteria rapidly disseminate and cause manifestations in the cardiovascular and nervous systems. It is an obligate human parasite.

Strain Nichols was isolated in 1912 from the cerebrospinal fluid of a patient with secondary syphilis. It has been passed in rabbits since 1912.


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