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Overview

Proteins4,940
Proteome IDiUP000000748
Taxonomy585397 - Escherichia coli O81 (strain ED1a)
StrainED1a
Last modifiedFebruary 27, 2018
Genome assembly and annotationi GCA_000026305.1 from ENA/EMBL
Pan proteomei This proteome is part of the Escherichia coli (strain K12) pan proteome (fasta)

Escherichia coli is a Gram-negative straight rod, which either uses peritrichous flagella for mobility or is nonmotile. It is a facultatively anaerobic chemoorganotroph capable of both respiratory and fermentative metabolism. E.coli serves a useful function in the body by suppressing the growth of harmful bacterial species and by synthesizing appreciable amounts of vitamins. It is an important component of the biosphere. It colonizes the lower gut of animals and survives when released to the natural environment, allowing widespread dissemination to new hosts. Pathogenic E.coli strains are responsible for infection of the enteric, urinary, pulmonary and nervous systems. Comparison of 20 E.coli/Shigella strains shows the core genome to be about 2000 genes while the pan-genome has over 18,000 genes. There are multiple, striking integration hotspots that are conserved across the genomes, corresponding to regions of abundant and parallel insertions and deletions of genetic material.

Strain ED1a was isolated from the feces of a healthy man who did not take antibiotics for at least six months before sampling. It represents a feces dominant and persistent (over a six month period) clone, is devoid of the main extraintestinal virulence genes and avirulent in a mouse model of extraintestinal infection. It is serogroup O81, phylogenetic group B2.

Componentsi

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Component nameGenome Accession(s)
Proteins
Chromosome4806
Plasmid pECOED137

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