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Overview

Proteome nameEscherichia coli O45:K1
Proteins4,805
Proteome IDiUP000000747
StrainS88 / ExPEC
Taxonomy585035 - Escherichia coli O45:K1 (strain S88 / ExPEC)
Last modifiedAugust 31, 2017
Genome assembly and annotationi GCA_000026285.2 from ENA/EMBL
Pan proteomei This proteome is part of the Escherichia coli MG1655 pan proteome (fasta)

Escherichia coli is a Gram-negative straight rod, which either uses peritrichous flagella for mobility or is nonmotile. It is a facultatively anaerobic chemoorganotroph capable of both respiratory and fermentative metabolism. E.coli serves a useful function in the body by suppressing the growth of harmful bacterial species and by synthesizing appreciable amounts of vitamins. It is an important component of the biosphere. It colonizes the lower gut of animals and survives when released to the natural environment, allowing widespread dissemination to new hosts. Pathogenic E.coli strains are responsible for infection of the enteric, urinary, pulmonary and nervous systems. Comparison of 20 E.coli/Shigella strains shows the core genome to be about 2000 genes while the pan-genome has over 18,000 genes. There are multiple, striking integration hotspots that are conserved across the genomes, corresponding to regions of abundant and parallel insertions and deletions of genetic material.

Strain S88 is an extraintestinal pathogenic E.coli strain (ExPEC) isolated from the cerebrospinal fluid of a late onset neonatal meningitis case in France in 1999. It is serotype O45:K1 and in phylogenetic group B2.

Componentsi

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Component nameGenome Accession(s)
Proteins
Chromosome4673
Plasmid pECOS88134