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Overview

Proteome nameMycobacterium sp. KMS - Reference proteome
Proteins5,893
Proteome IDiUP000000638
StrainKMS
Taxonomy189918 - Mycobacterium sp. (strain KMS)
Last modifiedFebruary 4, 2017
Genome assembly and annotationi GCA_000015405.1 from ENA/EMBL
Pan proteomei This proteome is part of the Mycobacterium sp. KMS pan proteome (fasta)

Mycobacteria belong to the order Actinomycetales that are Gram-positive, acid-fast, pleomorphic, non-motile rods characterized by distinctive cell surface mycolic acid derivatives. They are obligate aerobes. This isolate belongs to a fast-growing group and actually has a coccus morphology, whereas members of the slow-growing group of Mycobacteria are notorious for causing human and animal diseases.

Mycobacterium KMS was isolated from soil in Libby, Montana, USA, the site of a former lumber and plywood mill. The soil is contaminated by polycyclic aromatic hydrocarbons (PAH), and KMS is one of several indigenous mycobacteria isolated from this site that are able to degrade high molecular weight PAH including pyrene, however this isolate cannot degrade benzo(a)pyrene. Other Mycobacteria from this site include strain MCS (MYCSS) and strain JLS (MYCSJ). Strain KMS mineralizes small- and large-ring PAHs, in contrast to other PAH-degrading microbes and thus offers possibilities for bioremediation of PAHs. The genome sequence of the Mycobacterium isolate KMS will permit comparisons with the genomes of pathogenic isolates, as well as an understanding of the pathway for PAH degradation and survival mechanisms in polluted conditions (adapted from http://genome.jgi-psf.org/myc_k/myc_k.home.html).

Mycobacteria have an unusual outer membrane approximately 8nm thick, despite being considered Gram-positive. The outer membrane and the mycolic acid-arabinoglactan-peptidoglycan polymer form the cell wall, which constitutes an efficient permeability barrier in conjunction with the cell inner membrane.

Componentsi

DownloadView all proteins
Component nameGenome Accession(s)
Proteins
Chromosome5407
Plasmid pMKMS01278
Plasmid pMKMS02226

Publications

  1. "Complete sequence of plasmid pMKMS02 of Mycobacterium sp. KMS."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.
    , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Richardson P.
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
  2. "Complete sequence of chromosome of Mycobacterium sp. KMS."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.
    , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Richardson P.
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
  3. "Complete sequence of plasmid pMKMS01 of Mycobacterium sp. KMS."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.
    , Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Richardson P.
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases