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Proteome nameMus musculus C57BL/6J - Reference proteome
Proteome IDiUP000000589
Taxonomy10090 - Mus musculus
Last modifiedFebruary 19, 2017
Genome assemblyGCA_000001635.6

The house mouse (Mus musculus) is a common rodent that is distributed throughout the world. It has become a frequently used model for understanding human disease and development due to its small size, short life-cycle and rapid breeding cycle.

The mouse was the second mammal to have its genome sequenced. The mouse strain used for sequencing was C57BL/6J, which is the most widely used inbred strain. This strain is a permissive background for the expression of most mutations, but is resilient to many tumors.

C57BL/6J mice are susceptible to atherosclerosis, type 2 diabetes and diet-induced obesity. It also develops age-related hearing loss. 75% of the mouse genes are in 1:1 orthologous relationships to human genes and have most likely maintained their ancestral function in both species.

The reference proteome of Mus musculus is derived from the genome sequence of strain C57BL/6J that was published in 2009. The size of the genome is 2.6 Gb and it contains 20,210 predicted protein-coding genes.


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Component nameGenome Accession(s)
Chromosome 13136
Chromosome 23964
Chromosome 32494
Chromosome 42889
Chromosome 53443
Chromosome 62962
Chromosome 74909
Chromosome 82435
Chromosome 93215
Chromosome 102056
Chromosome 113504
Chromosome 121453
Chromosome 131486
Chromosome 141809
Chromosome 151509
Chromosome 161423
Chromosome 172072
Chromosome 18987
Chromosome 191349
Chromosome Y140
Chromosome X1739