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StatusReference proteome
Proteome IDiUP000000589
Taxonomy10090 - Mus musculus
Last modifiedMarch 13, 2018
Genome assembly and annotationi GCA_000001635.7 from Ensembl

The house mouse (Mus musculus) is a common rodent that is distributed throughout the world. It has become a frequently used model for understanding human disease and development due to its small size, short life-cycle and rapid breeding cycle.

The mouse was the second mammal to have its genome sequenced. The mouse strain used for sequencing was C57BL/6J, which is the most widely used inbred strain. This strain is a permissive background for the expression of most mutations, but is resilient to many tumors.

C57BL/6J mice are susceptible to atherosclerosis, type 2 diabetes and diet-induced obesity. It also develops age-related hearing loss. 75% of the mouse genes are in 1:1 orthologous relationships to human genes and have most likely maintained their ancestral function in both species.

The reference proteome of Mus musculus is derived from the genome sequence of strain C57BL/6J that was published in 2009. The size of the genome is 2.6 Gb and it contains 20,210 predicted protein-coding genes.


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Component nameGenome Accession(s)
Chromosome 13155
Chromosome 23988
Chromosome 32494
Chromosome 42922
Chromosome 53448
Chromosome 62980
Chromosome 74941
Chromosome 82433
Chromosome 93218
Chromosome 102433
Chromosome 113510
Chromosome 121861
Chromosome 131966
Chromosome 142241
Chromosome 151651
Chromosome 161437
Chromosome 172178
Chromosome 181024
Chromosome 191426
Chromosome Y140
Chromosome X1748