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Proteome nameMus musculus C57BL/6J - Reference proteome
Proteome IDiUP000000589
Taxonomy10090 - Mus musculus
Last modifiedDecember 1, 2017
Genome assembly and annotationi GCA_000001635.8 from Ensembl

The house mouse (Mus musculus) is a common rodent that is distributed throughout the world. It has become a frequently used model for understanding human disease and development due to its small size, short life-cycle and rapid breeding cycle.

The mouse was the second mammal to have its genome sequenced. The mouse strain used for sequencing was C57BL/6J, which is the most widely used inbred strain. This strain is a permissive background for the expression of most mutations, but is resilient to many tumors.

C57BL/6J mice are susceptible to atherosclerosis, type 2 diabetes and diet-induced obesity. It also develops age-related hearing loss. 75% of the mouse genes are in 1:1 orthologous relationships to human genes and have most likely maintained their ancestral function in both species.

The reference proteome of Mus musculus is derived from the genome sequence of strain C57BL/6J that was published in 2009. The size of the genome is 2.6 Gb and it contains 20,210 predicted protein-coding genes.


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Component nameGenome Accession(s)
Chromosome 13153
Chromosome 23958
Chromosome 32498
Chromosome 42914
Chromosome 53448
Chromosome 62962
Chromosome 74919
Chromosome 82430
Chromosome 93213
Chromosome 102433
Chromosome 113506
Chromosome 121862
Chromosome 131960
Chromosome 141960
Chromosome 151507
Chromosome 161421
Chromosome 172135
Chromosome 181024
Chromosome 191427
Chromosome Y140
Chromosome X1747