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Overview

Proteome nameMus musculus C57BL/6J - Reference proteome
Proteins52,539
Proteome IDiUP000000589
StrainC57BL/6J
Taxonomy10090 - Mus musculus
Last modifiedOctober 1, 2017
Genome assembly and annotationi GCA_000001635.8 from Ensembl
© calphotos.berkeley.edu

The house mouse (Mus musculus) is a common rodent that is distributed throughout the world. It has become a frequently used model for understanding human disease and development due to its small size, short life-cycle and rapid breeding cycle.

The mouse was the second mammal to have its genome sequenced. The mouse strain used for sequencing was C57BL/6J, which is the most widely used inbred strain. This strain is a permissive background for the expression of most mutations, but is resilient to many tumors.

C57BL/6J mice are susceptible to atherosclerosis, type 2 diabetes and diet-induced obesity. It also develops age-related hearing loss. 75% of the mouse genes are in 1:1 orthologous relationships to human genes and have most likely maintained their ancestral function in both species.

The reference proteome of Mus musculus is derived from the genome sequence of strain C57BL/6J that was published in 2009. The size of the genome is 2.6 Gb and it contains 20,210 predicted protein-coding genes.

Componentsi

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Component nameGenome Accession(s)
Proteins
Chromosome 13151
Chromosome 23960
Chromosome 32498
Chromosome 42914
Chromosome 53446
Chromosome 62962
Chromosome 74919
Chromosome 82430
Chromosome 93214
Chromosome 102431
Chromosome 113506
Chromosome 121862
Chromosome 131948
Chromosome 141952
Chromosome 151511
Chromosome 161421
Chromosome 172134
Chromosome 181023
Chromosome 191424
Chromosome Y140
Chromosome X1748
Unplaced
1975
Mitochondrion13