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Overview

Proteome nameBrucella abortus 1
Proteins3,077
Proteome IDiUP000000540
Strain9-941
Taxonomy262698 - Brucella abortus biovar 1 (strain 9-941)
Last modifiedFebruary 11, 2017
Genome assembly and annotationi GCA_000008145.1 from ENA/EMBL
Pan proteomei This proteome is part of the Brucella abortus 2308 pan proteome (fasta)

The genus Brucella is comprised mostly of mammalian pathogens, which due to their low infectious does, aerosol transmission and treatment difficulty are classified as potential bioterrorism agents. Brucellosis is a major infectious disease for both human and animals. Several Brucella species (B.abortus, B.melitensis and B.suis) have been isolated from many different animals. All three Brucella species cause a severe human disease characterized in its acute phase by undulant fever and in its chronic phase by damage of different organs. Brucellosis is a major problem in the Mediterranean region and parts of Asia, Africa and Latin America. When the infection is localized to the brain or the heart, it can result in a fatal meningitidis or fatal endocarditis, respectively. Brucella abortus is responsible not only for the human affection but also for the brucellosis of cattle, also known as "contagious abortion". Brucella abortus infection in cattle is responsible for abortion or premature calving. The foetus, placenta and uterine fluid contain large quantities of bacteria which can infect other cattle. The organism continues to be excreted in the milk; in the past humans were frequently infected through drinking unpasteurised milk. Human brucellosis is treatable with antibiotics whereas animals can be vaccinated. Although Brucellae contain a large set of flagellar genes, they display a species-specific gene inactivation and consequently are nonmotile.

Componentsi

DownloadView all proteins
Component nameGenome Accession(s)
Proteins
Chromosome I2023
Chromosome II1056

Publications

  1. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
    Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
    J. Bacteriol. 2005:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]