Proteomes - Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
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Overview
| Proteome name | Komagataella phaffii (strain GS115 / ATCC 20864) Yeast Pichia pastoris - Reference proteome |
| Proteins | 5,073 |
| Proteome IDi | UP000000314 |
| Strain | GS115 / ATCC 20864 |
| Taxonomy | 644223 - Komagataella phaffii (strain GS115 / ATCC 20864) |
| Last modified | February 4, 2017 |
| Genome assembly and annotationi | GCA_000027005.1 from ENA/EMBL |
| Pan proteomei | This proteome is part of the Komagataella phaffii (strain GS115 / ATCC 20864) Yeast Pichia pastoris pan proteome (fasta) |
Pichia pastoris has been reassigned to the genus Komagataella after phylogenetic analysis of gene sequences, and split into three species, K. pastoris, K. phaffii, and K. pseudopastoris. These species are facultative methylotrophic yeasts: they are able to use single carbon compounds (e.g. methanol or methane) or multi-carbon compounds with no carbon-carbon bonds (e.g. dimethyl ether or dimethylamine) as a food source.
Pichia pastoris has been used extensively as an expression system for protein production because of its high growth rate, low cost of culture, and because it is able to produce proteins with disulfide bonds and glycosylation.
The genome sequence was published in 2009 for Komagataella pastoris strain GS115. It consists of 9.4Mb in 4 chromosomes with 5,313 predicted protein-coding genes.
Componentsi
DownloadView all proteins| Chromosome 1 | 1538 | |||
| Chromosome 1, Contig 34 | 34 | |||
| Chromosome 2 | 1333 | |||
| Chromosome 3 | 1198 | |||
| Chromosome 4 | 971 | |||
| Chromosome 4, Contig 157 | 3 | |||
Publications
- "Genome sequence of the recombinant protein production host Pichia pastoris."
De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S., Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.
Nat. Biotechnol. 2009:561-566(2009) [PubMed] [Europe PMC] [Abstract]