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Latest from the prokaryotic world: bacterial Cas9, a new tool for genome engineering | Cross-references to ChiTaRS and SABIO-RK | Removal of cross-references to 8 2D gel databases and AGD
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Prokaryotes do it too: CRISPR, an RNA-based adaptive immune system in UniProt | Cross-references to GenomeRNAi, Protein Data Bank Japan, RCSB PDB and UniPathway
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Who wants to be a millionaire? The first million HAMAP-annotated entries in UniProtKB/TrEMBL | Cross-references to KO
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Killing myself softly: Bacterial and Archaeal Type II Toxin-Antitoxin modules (TA) | Provision of complete proteome data sets for IPI species by UniProt
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Program › Prokaryotic protein annotation program
Statistics
UniProt release 2013_05 - May-01, 2013 contains a total of 540,052 reviewed entries, which includes 347,875 entries from 2,076 species of Bacteria and Archae.
Statistics for complete bacterial proteomes
Statistics for complete archaeal proteomes
Escherichia coli (strain K12) - 4,431 reviewed entries (HAMAP complete proteome)
| Evidence for the existence of protein | Percentage of entries |
|---|---|
| at protein level | 61.1% |
| at transcript level | 2.9% |
| inferred from homology | 16.3% |
| predicted | 16.4% |
| uncertain | 3.4% |
| Annotation categories | Entries with | Number of annotations | Coverage |
|---|---|---|---|
| PubMed citations | 4,399 | 6,890 unique | 99.3% |
| General annotation | 4,141 | 19,320 | 93.5% |
| Function | 2,676 | 2,776 | 60.4% |
| Catalytic activity | 1,239 | 1,389 | 28% |
| Subcellular location | 2,023 | 19,320 | 45.7% |
| Sequence annotation | 3,609 | 59,850 | 81.4% |
| Amino acid modifications | 471 | 781 | 10.6% |
| Natural Variant | 132 | 434 | 3% |
| Cross-references | 4,431 | 177,681 | 100% |
| EMBL | 4,431 | 16,128 | 100% |
| InterPro | 4,166 | 12,392 | 94% |
| PDB | 1,272 | 9,185 | 28.7% |
| RefSeq | 4,374 | 9,074 | 98.7% |
100% of reviewed Escherichia coli (strain K12) entries are annotated with at least one keyword.
87.5% of reviewed Escherichia coli (strain K12) entries are annotated with at least one GO (Gene Ontology) term.
Bacillus subtilis - 4,188 reviewed entries (HAMAP complete proteome)
| Evidence for the existence of protein | Percentage of entries |
|---|---|
| at protein level | 29.6% |
| at transcript level | 8.7% |
| inferred from homology | 32.1% |
| predicted | 29.5% |
| uncertain | 0.1% |
| Annotation categories | Entries with | Number of annotations | Coverage |
|---|---|---|---|
| PubMed citations | 4,188 | 2,018 unique | 100% |
| General annotation | 3,543 | 14,066 | 84.6% |
| Function | 1,844 | 1,890 | 44% |
| Catalytic activity | 953 | 1,045 | 22.8% |
| Subcellular location | 1,754 | 14,066 | 41.9% |
| Sequence annotation | 3,201 | 26,479 | 76.4% |
| Amino acid modifications | 388 | 592 | 9.3% |
| Natural Variant | 42 | 141 | 1% |
| Cross-references | 4,188 | 104,484 | 100% |
| EMBL | 4,188 | 9,177 | 100% |
| InterPro | 3,638 | 10,254 | 86.9% |
| PDB | 468 | 1,076 | 11.2% |
| RefSeq | 4,136 | 4,137 | 98.8% |
100% of reviewed Bacillus subtilis entries are annotated with at least one keyword.
96.6% of reviewed Bacillus subtilis entries are annotated with at least one GO (Gene Ontology) term.
Mycobacterium tuberculosis - 2,022 reviewed entries (HAMAP complete proteome)
| Evidence for the existence of protein | Percentage of entries |
|---|---|
| at protein level | 36.4% |
| at transcript level | 4.2% |
| inferred from homology | 43.2% |
| predicted | 16.1% |
| uncertain | 0.1% |
| Annotation categories | Entries with | Number of annotations | Coverage |
|---|---|---|---|
| PubMed citations | 2,018 | 989 unique | 99.8% |
| General annotation | 1,912 | 8,642 | 94.6% |
| Function | 1,111 | 1,160 | 54.9% |
| Catalytic activity | 687 | 756 | 34% |
| Subcellular location | 740 | 8,642 | 36.6% |
| Sequence annotation | 1,562 | 15,990 | 77.3% |
| Amino acid modifications | 237 | 342 | 11.7% |
| Natural Variant | 50 | 120 | 2.5% |
| Cross-references | 2,019 | 64,774 | 99.9% |
| EMBL | 2,018 | 6,028 | 99.8% |
| InterPro | 1,864 | 5,528 | 92.2% |
| PDB | 326 | 1,106 | 16.1% |
| RefSeq | 1,993 | 5,794 | 98.6% |
100% of reviewed Mycobacterium tuberculosis entries are annotated with at least one keyword.
91.6% of reviewed Mycobacterium tuberculosis entries are annotated with at least one GO (Gene Ontology) term.
