Release 7.4

Published April 4, 2006

Headlines

Complete proteome for Drosophila melanogaster

The keyword complete proteome has been added to all Drosophila melanogaster entries in to UniProtKB. This is the second metazoa to have the keyword added; the other one being Caenorhabditis elegans. Eleven other eukaryotes have the keyword added; ten complete fungal genomes and Plasmodium yoelii yoelii. The presence of this keyword allows easy retrieval of a complete non-redundant set of proteins from the Drosophila melanogaster genome (nuclear and mitochondrial) across the Swiss-Prot and TrEMBL sections of the UniProt Knowledgebase. To add the keyword, all fruit fly UniProtKB/Swiss-Prot entries have been updated for addition of the genome project reference (Adams et al, 2002, Science 287:2185-2195), along with other relevant updates as appropriate.

UniProtKB Release 7.4 has 2361 Drosophila melanogaster entries in UniProtKB/Swiss-Prot and 25453 entries in UniProtKB/TrEMBL. Addition of the keyword 'Complete proteome' will allow the retrieval of the complete nonredundant proteome consisting of 16229 entries, 2329 from UniProtKB/Swiss-Prot and 13900 from UniProtKB/TrEMBL. The proteome can also be downloaded from our FTP server or from Integr8.

UniProtKB News

Cross-references to UniGene

Cross-references have been added to UniGene, a sequence database which provides the automatic partition of GenBank sequences into a non-redundant set of gene-oriented clusters. Each UniGene cluster contains sequences that represent a unique gene, as well as related information such as the tissue types in which the gene has been expressed and map location.

Examples:

AC   Q9ZNT7;
DR   UniGene; At.24021.
DR   UniGene; At.64486.

AC   P59990;
DR   UniGene; Hs.505267.