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UniProt release 2.2

Published July 30, 2004

UniProtKB News

Changes concerning the controlled vocabulary for PTMs

We are continuously overhauling the annotation of post-translational modifications (PTMs). For the feature key MOD_RES, the new introduced controlled vocabularies for PTMs (PTMlist.txt) are:

  • Methylation: All entries with annotated methylation sites have the keyword Methylation.

     N6,N6,N6-trimethyl-5-hydroxylysine
     N6-poly(methylaminopropyl)lysine
    
  • Hydroxylation: All entries with annotated hydroxylation sites have the keyword Hydroxylation.

     3-hydroxyproline
     4-hydroxyarginine
    
  • Unidentified N-terminal blocking modifications:

     Blocked amino end (Leu)
    
  • Other new controlled vocabularies for PTMs that are annotated with the feature key MOD_RES:

     Glycine radical (Keyword: Organic radical) 
     Pentaglycyl murein peptidoglycan amidated alanine (Keyword: Peptidoglycan-anchor)
     Tryptophylquinone