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UniProt release 1.9

Published May 4, 2004

Headlines

Swiss-Prot reaches 150'000 entries

With this release the number of Swiss-Prot entries has reached the 150'000 mark. It took about 9.5 years to reach the 50'000 entries mark (January 1996), almost 6 more years to reach 100'000 entries (September 2001) and about 2.5 years to the current 150'000 entries.

The continuous increase in the speed of annotation is due to a number of factors among which the increase in the number of annotators working for Swiss-Prot at SIB and EBI, increase in the productivity of the work of these annotators, the implementation and improvement of software tools that help to automate some annotation tasks, facilitated access to many third party resources, and the gradual rise in quality of the underlying DNA sequences as well as the quality of genomic and cDNA annotation.

UniProtKB News

Changes concerning the controlled vocabulary for PTMs

We are continuously overhauling the annotation of post-translational modifications (PTMs). Methylation sites are described in the description field of the feature key MOD_RES, all entries with such a site contain the keyword 'Methylation'. The initially defined controlled vocabulary for methylation sites is listed below:

N-methylalanine
N,N,N-trimethylalanine
Omega-N-methylated arginine
Omega-N-methylarginine
Asymmetric dimethylarginine
Symmetric dimethylarginine
5-methylarginine
N5-methylarginine
N4-methylasparagine
N4,N4-dimethylasparagine
S-methylcysteine
Cysteine methyl ester
2-methylglutamine
N5-methylglutamine
Glutamate methyl ester (Gln)
Glutamate methyl ester (Glu)
Methylhistidine
Pros-methylhistidine
Tele-methylhistidine
N-methylisoleucine
N-methylleucine
Leucine methyl ester
N6-methylated lysine
N6-methyllysine
N6,N6-dimethyllysine
N6,N6,N6-trimethyllysine
Lysine methyl ester
N-methylmethionine
N-methylphenylalanine
N,N-dimethylproline
N-methyltyrosine

Changes concerning keywords

Deleted keyword:

  • Egg white