TrEMBL release 1.0

First release of TREMBL, a protein sequence database supplementing 
the SWISS-PROT Protein Sequence Data Bank


INTRODUCTION
============

TREMBL is a protein sequence database supplementing the SWISS-PROT Protein
Sequence Data Bank. TREMBL contains the translations of all coding 
sequences (CDS) present in the EMBL Nucleotide Sequence Database not yet
integrated in SWISS-PROT. TREMBL can be considered as a preliminary 
section of SWISS-PROT. For all TREMBL entries which should finally be 
upgraded to the standard SWISS-PROT quality, SWISS-PROT accession numbers 
have been assigned.


FIRST RELEASE OF TREMBL
=======================

This TREMBL release is created from the EMBL Nucleotide Sequence Database
release 48 and contains 104'962 sequence entries, comprising 28'063'108 
amino acids. TREMBL release 1 will be distributed with SWISS-PROT release 34.


TREMBL is split in two main sections; SP-TREMBL and REM-TREMBL:

SP-TREMBL (SWISS-PROT TREMBL) contains the entries (86'040) which should be 
incorporated into SWISS-PROT. SWISS-PROT accession numbers have been assigned
for all SP-TREMBL entries. 

SP-TREMBL is organized in subsections:

fun.dat (Fungi):                3367 entries
hum.dat (Human):                4322 entries
inv.dat (Invertebrates):       11920 entries
mam.dat (Other Mammals):        1768 entries
mhc.dat (MHC proteins):         2050 entries
org.dat (Organelles):           6285 entries
phg.dat (Bacteriophages):        866 entries
pln.dat (Plants):               5524 entries
pro.dat (Prokaryotes):         17222 entries
rod.dat (Rodents):              4573 entries
vrl.dat (Viruses):             26042 entries
vrt.dat (Other Vertebrates):    2101 entries


REM-TREMBL (REMaining TREMBL) contains the entries (19'255) that we do 
not want to include in SWISS-PROT. 


ACCESS/DATA DISTRIBUTION
========================

FTP server:     ftp.ebi.ac.uk/pub/databases/trembl
SRS server:     http://www.ebi.ac.uk/srs/srsc

TREMBL is also available on the SWISS-PROT CD-ROM.
SP-TREMBL will be searchable on the FASTA and BLITZ servers of the EBI.



TREMBL HAS BEEN PREPARED BY:
============================

Rolf Apweiler, Alain Gateau, Vivien Junker, Stephanie Kappus, Fiona Lang, 
Nicoletta Mitaritonna and Claire O'Donovan at the EMBL Outstation - European 
Bioinformatics Institute (EBI) in Hinxton, UK;
Amos Bairoch at the Medical Biochemistry Department of the University 
of Geneva, Switzerland.


=======================================================================
Rolf Apweiler                           | SWISS-PROT Coordinator
EMBL Outstation                         | Email:apweiler@ebi.ac.uk
European Bioinformatics Institute (EBI) | URL:  http://www.ebi.ac.uk
Wellcome Trust Genome Campus, Hinxton   | Tel:  +44 (1223) 494435
Cambridge CB10 1SD, UK                  | Fax:  +44 (1223) 494968
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