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Alternative sequence

Last modified September 9, 2013

This subsection of the ‘Sequence annotation (Features)’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.

We describe the amino acid changes and the alternative isoform in the ‘Description’ field of each ‘Alternative sequence’ subsection. Note that several ‘Alternative sequence’ subsections may be required to completely describe a given isoform. Conversely, a particular sequence alteration may be found in more than one isoform.
Example: P04150

Each ‘Alternative sequence’ subsection has stable feature identifiers (FTIds).

General information concerning alternative protein sequence isoforms, such as the number of isoforms and the level of experimental support for each isoform, is provided in the ‘Alternative products’ section of the ‘General annotation (Comments)’ section.

Related keywods: Alternative splicing, Alternative initiation, Alternative promoter usage,
Ribosomal frameshifting.

Link to relevant documents