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Sequence processing

Last modified September 9, 2013

This subsection of the ‘Protein attributes’ section indicates if the canonical sequence displayed by default in the entry is in its mature form or if it represents the precursor.

The canonical sequence is a precursor

If the canonical sequence requires processing to become mature, the following comment is found in the ‘Sequence processing’ subsection: ‘The displayed sequence is further processed into a mature form.’
Example: P01308

Processing of the precursor includes signal peptide and propeptide cleavage, transit peptide cleavage or initiator methionine cleavage. The processing required for maturation is described in the ‘Molecular processing’ subsection of the ‘Sequence annotation (Features)’ section.
Examples: P01308, Q99K67, P68250

Other case

If there is no evidence for further processing (e.g. the canonical sequence represents the mature form), there is no ‘Sequence processing’ subsection.
Example: O60437

Remark: There is also no ‘Sequence processing’ subsection if the canonical sequence is not yet known to require further processing.