Last modified September 9, 2013
This subsection of the ‘General annotation (Comments)’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).
Transcriptional regulation by transcription factors or repressors is only rarely described in UniProtKB. In some specific cases, however, we indicate such information without going into details.
This subsection does not describe the regulation of activity, which can be found in the subsection ‘Enzyme regulation’ for enzymes, and in other ‘General annotation (Comments)’ subsections, such as ‘Function’ or ‘Miscellaneous’, for other proteins.