90 items
› Restrict list of documents to category: alternative_products, binary_interactions, cross_references, entry_information, general_annotation, names_origin, ontologies, protein_attributes, references, sequence_annotation, sequences, web_resources
| Description of the different proteins generated from the same gene |
| Information relevant to binary protein-protein interactions |
| Cross-references that point to data collections other than UniProtKB |
Entry information
| Accession | Provides a stable way of identifying UniProtKB entries |
|---|---|
| Entry history | Dates of creation and modification and version information |
| Entry status | Indicates if the entry has been manually reviewed (UniProtKB/Swiss-Prot) or not (UniProtKB/TrEMBL) |
| Position-independent annotation | |
| Non-experimental qualifiers | Non-experimental qualifiers indicate that the information given is not based on experimental findings. |
|---|---|
| Function | General description of the function(s) of a protein |
| Catalytic activity | Description of the reaction(s) catalyzed by an enzyme |
| Cofactor | Description of non-protein substance required by an enzyme to be active |
| Enzyme regulation | Description of an enzyme regulatory mechanism |
| Biophysicochemical properties | Description of biophysical and physicochemical properties |
| Subunit structure | Description of the quaternary structure of a protein |
| Pathway | Description of associated metabolic pathways |
| Subcellular location | Description of the subcellular location of the mature protein |
| Tissue specificity | Description of the expression of a gene in different tissues |
| Developmental stage | Description of how the expression of a gene varies according to the stage of cell, tissue or organism development |
| Induction | Description of the effects of environmental factors on the gene expression |
| Domain | Description of the domain(s) present in a protein |
| Post-translational modification | Description of post-translational modifications |
| RNA editing | Description of amino acid change(s) due to RNA editing |
| Mass spectrometry | Information derived from mass spectrometry experiments |
| Polymorphism | Description of polymorphism(s) |
| Involvement in disease | Description of the disease(s) associated with the deficiency of a protein |
| Disruption phenotype | Description of the effects caused by the disruption of a protein-encoding gene. |
| Allergenic properties | Information relevant to allergenic proteins |
| Toxic dose | Lethal, paralytic, or effect dose, or lethal concentration of a toxin |
| Biotechnological use | Description of the use of a specific protein in a biotechnological process |
| Pharmaceutical use | Description of the use of a protein as a pharmaceutical drug |
| Miscellaneous | Any relevant information that doesn't fit in any other defined sections |
| Sequence similarities | Description of the sequence similaritie(s) with other proteins |
| Caution | Warning about possible errors and/or grounds for confusion |
| Sequence caution | Warning about possible errors related to the protein sequence |
Names origin
| Entry name | Mnemonic identifier for a UniProtKB entry |
|---|---|
| Protein names | Name and synonyms of the protein |
| Gene names | Name(s) of the gene(s) that code for the protein |
| Encoded on | Organelle or plasmid gene source |
| Organism | Name of the source organism |
| Taxonomic identifier | NCBI unique identifier for the source organism |
| Taxonomic lineage | Taxonomic classification of the source organism |
| Virus host | The species that can be infected by a specific virus |
Ontologies
| Keywords | List of controlled vocabulary which summarises the content of an entry |
|---|---|
| Gene Ontology (GO) | Selection of Gene Ontology (GO) terms |
Protein attributes
| Sequence length | Sequence length |
|---|---|
| Sequence status | Indicates if the protein sequence is complete or not |
| Sequence processing | Indicates if the mature form of a protein is derived by processing of a precursor |
| Protein existence | Level of evidence that supports the existence of the protein concerned |
| Literature citations |
| Position-dependent annotation | |
| Non-experimental qualifiers | Non-experimental qualifiers indicate that the information given is not based on experimental findings. |
|---|---|
| Initiator methionine | Cleaved initiator methionine |
| Signal | Sequence targeting proteins to the secretory pathway or periplasmic space |
| Propeptide | Part of a protein that is cleaved during maturation or activation |
| Transit peptide | Extent of a transit peptide for organelle targeting |
| Chain | Extent of a polypeptide chain in the mature protein |
| Peptide | Extent of an active peptide in the mature protein |
| Topological domain | Location of non-membrane regions of membrane-spanning proteins |
| Transmembrane | Extent of a membrane-spanning region |
| Domain | Denotes the position and type of each modular protein domain |
| Repeat | Denotes the positions of repeated sequence motifs or repeated domains |
| Calcium binding | Denotes the position(s) of calcium binding region(s) within the protein |
| Zinc finger | Denotes the position(s) and type(s) of zinc fingers within the protein |
| DNA binding | Denotes the position and type of a DNA-binding domain |
| Nucleotide binding | Nucleotide phosphate binding region |
| Region | Region of interest in the sequence |
| Coiled coil | Denotes the positions of regions of coiled coil within the protein |
| Motif | Short (up to 20 amino acids) sequence motif of biological interest |
| Compositional bias | Region of compositional bias in the protein |
| Active site | Amino acid(s) directly involved in the activity of an enzyme |
| Metal binding | Binding site for a metal ion |
| Binding site | Binding site for any chemical group (co-enzyme, prosthetic group, etc.) |
| Site | Any interesting single amino acid site on the sequence |
| Non-standard residue | Occurence of non-standard amino acids (selenocysteine and pyrrolysine) in the protein sequence |
| Modified residue | Modified residues excluding lipids, glycans and protein crosslinks |
| Lipidation | Covalently attached lipid group(s) |
| Glycosylation | Covalently attached glycan group(s) |
| Disulfide bond | Cysteine residues participating in disulfide bonds |
| Cross-link | Residues participating in covalent linkage(s) between proteins |
| Alternative sequence | Amino acid change(s) producing alternate protein isoforms |
| Natural variant | Description of a natural variant of the protein |
| Mutagenesis | Site which has been experimentally altered by mutagenesis |
| Sequence uncertainty | Regions of uncertainty in the sequence |
| Sequence conflict | Description of sequence discrepancies of unknown origin |
| Non-adjacent residues | Indicates that two residues in a sequence are not consecutive |
| Non-terminal residue | The sequence is incomplete. Indicate that a residue is not the terminal residue of the complete protein. |
| Helix | Helical regions within the experimentally determined protein structure |
| Turn | Turns within the experimentally determined protein structure |
| Beta strand | Beta strand regions within the experimentally determined protein structure |
| Protein sequence data for all described protein isoforms |
| Links to related web resource(s) or database(s) |
