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Graphical

ExosomeSecreted

Definition

Exosomes are 30-120 nm microvesicles of endocytic origin secreted by most cell types and found in abundance in body fluids, including blood, saliva, urine, and breast milk. They contain various molecular constituents of their cell of origin, including proteins and nucleic acids, and carry this cargo between diverse locations in the body. These microvesicles form by budding into the lumen of the multivesicular bodies (MVBs) and are released to extracellular fluids by fusion of MVBs with the plasma membrane.

Synonyms

Extracellular vesicular exosome

Category

› Cellular component

GOi

extracellular exosome [ GO:0070062 ]