Cellular component
PML body
| Definition | The PML bodies are dynamic nuclear protein aggregates interspersed between chromatin. These punctate nuclear structures are call PML bodies because the PML gene is essential for their formation. These discrete nuclear foci, 0.2-1.0 micrometer wide, are present in most mammalian cell nuclei and typically number 1 to 30 bodies per nucleus, depending on the cell type, cell-cycle phase and differentiation stage. Recent evidence implies that, although they appear to be uniform, PML-NBs are structurally and functionally heterogeneous and are dynamic structures. |
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| Synonyms |
PML-nuclear body
PML-NB
Promyelocytic leukemia nuclear body
Promyelocytic leukaemia nuclear body
Nuclear domains-10
ND10
Kremer body
PML oncogenic domain
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| Category | › Cellular component
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| GO | › PML body [ GO:0016605 ]
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| Graphical | 
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