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Cellular component Kinetochore

    • Format
    DefinitionThe kinetochore is a protein complex assembled on the centromeric region of DNA. It provides the major attachement point for the spindle microtubules during mitotic or meiotic division to pull the chromosomes apart. In monocentric chromosomes, the kinetochores of point centromeres bind a single microtubule and the larger kinetochores of regional centromeres interact with a number of microtubules. In holocentric chromosomes, the kinetochores bind the diffuse centromere along the length of the chromosomes.
    Synonyms
    Category› Cellular component
    KeywordsKinetochore
    GOicondensed chromosome kinetochore [ GO:0000777 ]
    Graphical ChromosomeCentromereKinetochore