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Graphical

Secretory vesicleAcrosomeCytoplasmic vesicle

Definition

The acrosome is a large lysosome-like vesicle overlying the sperm nucleus. This spermatid specific organelle, derived from the Golgi during spermatogenesis, contains both unique acrosomal enzymes and common enzymes associated with lysosomes in somatic cells. Only sperm that have undergone the acrosome reaction can fuse with egg plasma membrane. The acrosome reaction is characterized by multiple fusions of the outer acrosomal membrane with the sperm cell membrane.

Synonyms

Acrosomal vesicle

Category

› Cellular component

GOi

acrosomal vesicle [ GO:0001669 ]