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Keyword - Eukaryotic host translation shutoff by virus (KW-1193)

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Definition

Viral protein involved in inhibiting the host translational machinery to shutoff cellular gene expression. This gives virus transcripts a competitive edge to use the hijacked translation machinery. Preventing the expression of host proteins is also a strategy to counteract the antiviral response. Several virus are known to inhibit host translation mostly by inactivating translation factors.

Category

Biological process

GOi

suppression by virus of host translation [ GO:0039604 ]

Graphical

Host-virus interactionHost gene expression shutoff by virusEukaryotic host translation shutoff by virusEukaryotic host gene expression shutoff by virusBiological process