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Keyword - Eukaryotic host transcription shutoff by virus (KW-1191)

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Viral protein involved in inhibiting host transcription to ensure the shutoff of cellular proteins expression and give virus transcripts a competitive edge for access to the cellular translation machinery. Preventing the expression of host proteins is also a strategy to counteract the antiviral response. Inhibition of transcription can be performed by interfering with host RNA pol-II function or interfering with general transcription factors.


Biological process


suppression by virus of host transcription [ GO:0039653 ]


Host-virus interactionHost gene expression shutoff by virusEukaryotic host transcription shutoff by virusEukaryotic host gene expression shutoff by virusBiological process