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Keyword Decay of host mRNAs by virus

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DefinitionViral protein involved in the degradation of host mRNAs. Viruses have evolved ways of degrading host mRNAs to inhibit cellular translation. This global inhibition of cellular protein synthesis serves to ensure maximal viral gene expression and to evade host immune response. Decay of host mRNAs can be achieved by endonucleotic RNA cleavage or associated with PABPC1 nuclear relocalization.
CategoryBiological process
GraphicalDecay of host mRNAs by virusBiological processHost gene expression shutoff by virusHost mRNA suppression by virusHost-virus interaction
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BroaderHost mRNA suppression by virus