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Keyword Inhibition of host transcription initiation by virus

UniProtKB (11) rdf/xml obo
DefinitionViral protein involved in the disruption of the host transcriptional machinery. Viruses have evolved ways of interacting with the cellular preinitiation complex (PIC) to shutoff host transcription initiation. For example, the TATA binding protein and TFIIH are targeted by some viral proteins and thus cannot assemble properly to form a functional PIC.
CategoryBiological process
GraphicalBiological processHost transcription shutoff by virusHost gene expression shutoff by virusInhibition of host transcription initiation by virusHost-virus interaction
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BroaderHost transcription shutoff by virus