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Keyword Inhibition of host mRNA nuclear export by virus

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DefinitionViral protein involved in the disruption of the mRNA nuclear export machinery. Viruses have evolved ways of interacting with the nuclear export machinery to inhibit cellular translation and maximize the expression of their own mRNAs. This global inhibition of cellular protein synthesis serves to ensure maximal viral gene expression and to evade host immune response.
CategoryBiological process
GraphicalBiological processHost gene expression shutoff by virusInhibition of host mRNA nuclear export by virusHost mRNA suppression by virusHost-virus interaction
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BroaderHost mRNA suppression by virus