Keyword
Inhibition of host MDA5 by virus
| Definition | Viral protein involved in the evasion of host innate defense by inhibiting the IFIH1/MDA5 protein. Upon recognition of long viral dsRNAs, IFIH1/MDA5 initiates an antiviral signaling cascade by interacting with downstream partners. Some viral proteins including paramyxovirus V proteins interact with IFIH1/MDA5 and blocks its binding with its downstream partner MAVS. |
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| Category |
› Biological process
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| Graphical | 
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