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Keyword Inhibition of host complement factors by virus

UniProtKB (23,636) rdf/xml obo
DefinitionViral protein involved in the evasion of host humoral response by inhibiting the complement factors. The activation of complement involves the sequential proteolyis of proteins to generate enzymes with catalytic activities. The biological functions of the complement include opsonization, inflammation, lysis of immune complexes, or enhancement of the humoral immune response. Some herpesviruses, poxviruses and retroviruses mimic or interact with complement regulatory proteins to block complement activation and neutralization of virus particles.
CategoryBiological process
GraphicalBiological processInhibition of host complement factors by virusViral immunoevasionHost-virus interaction
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BroaderViral immunoevasion