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Keyword - Activation of host autophagy by virus (KW-1072)

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Broader

Definition

Viral protein involved in the activation of host autophagy. Autophagy is a major intracellular pathway in the delivery of cytoplasmic material to lysosomes for degradation. It is also essential for the removal of pathogenic protein aggregates from the cell during infection. Although autophagy is clearly important for antiviral immune response, it can also be activated by viruses and serves as platform for viral replication. Some viruses such as poliovirus, use the autophagic pathway as a nonlytic mechanism for viral release.

Category

Biological process

GOi

induction by virus of host autophagy [ GO:0039520 ]

Graphical

Activation of host autophagy by virusHost-virus interactionBiological process