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Keyword - Interferon antiviral system evasion (KW-0922)

Definition

Viral protein which prevents the activation of the antiviral state induced by interferon (IFN) in the host cell, thereby allowing the virus to replicate optimally. The antiviral state is the result of a signaling pathway induced by IFN-alpha or IFN-beta following viral infection. It leads to the transcription of various cellular antiviral genes coding for host defense proteins.

Synonyms

  • Antiviral state evasion
  • Interferon response evasion

Category

Biological process

GOi

evasion or tolerance by virus of host immune response [ GO:0030683 ]

Graphical

Interferon antiviral system evasionBiological process