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Keyword - Notch signaling pathway (KW-0914)

Definition

Protein involved in the Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Notch proteins are transmembrane receptors, which are cleaved by the gamma-secretase complex upon activation and released from the cell membrane and turn into transcriptional activators after their association with SU(H) proteins.

Category

Biological process

GOi

Notch signaling pathway [ GO:0007219 ]

Graphical

Notch signaling pathwayBiological process