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Keyword - Ubl conjugation pathway (KW-0833)

Definition

Protein involved in ubiquitin-like modifier processing, activation, conjugation or deconjugation such as Ubl-activating enzymes (E1s), Ubl-conjugating enzymes (E2s), Ubl-protein ligases (E3s), some thiol proteases (Ubiquitin carboxyl-terminal hydrolases (UCH), Ubiquitin-specific processing proteases (UBP) and ubiquitin-like proteases) and the ubiquitin-like modifier proteins. Besides signaling proteolysis, ubiquitination for example can be a signal for trafficking, kinase activation and other nonproteolytic fates.

Synonyms

  • Ubiquitin conjugation pathway
  • Ubiquitin-like modifier conjugation pathway

Category

Biological process

Graphical

Ubl conjugation pathwayBiological process