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Keyword - Ubiquinone (KW-0830)

Definition

Protein which interacts with ubiquinone. This fat soluble benzoquinone has a long isoprenoid side chain, which varies in length depending on the species. For example, S.cerevisiae has CoQ-6, E.coli has CoQ-8, rat and R.capsulatus have CoQ-9 and S.pombe, G.suboxydans and humans have CoQ-10. Ubiquinone is a carrier of hydrogen atoms (protons plus electrons) and functions as an ubiquitous coenzyme in redox reactions, where it is first reduced to the enzyme-bound intermediate radical semiquinone and in a second reduction to ubiquinol (Dihydroquinone; CoQH2). Ubiquinone is not tightly bound or covalently linked to a protein complex but is very mobile.

Synonyms

  • Coenzyme Q
  • CoQ

Category

Ligand

Graphical

LigandUbiquinone