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Keyword - Host cell lysis by virus (KW-0578)

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Broader

Definition

Viral protein involved in the lysis of the host cell allowing the release of mature, newly formed virions. Viruses use different way to lyse their host cell. They can express viroporins as Adenoviridae or Picornaviridae do in the late phase of infection. Phycodnaviridae for their part seem to express lytic phospholipids. In dsDNA prokaryotic viruses, lysis-specific proteins are expressed: a holin, which permeabilizes the inner membrane and an endolysin which then gains access to and degrades the host peptidoglycans. Some bacterioviruses express a signal-containing endolysin and thus do not need the holin function.

Category

Biological process

GOi

cytolysis by virus of host cell [ GO:0044659 ]

Graphical

Host cell lysis by virusViral release from host cellCytolysisBiological process