Keyword
Li-Fraumeni syndrome
| Definition | Protein which, if defective, causes Li-Fraumeni syndrome (LFS), an autosomal dominant familial cancer predisposition syndrome associated with soft-tissue sarcoma, breast cancer, leukemia, osteosarcoma, melanoma, and cancer of the colon, pancreas, adrenal cortex and brain. Individuals with LFS are at increased risk for developing multiple primary cancers. |
|---|
| Synonyms |
LFS
Sarcoma family syndrome of Li and Fraumeni
SBLA syndrome
|
|---|
| Category |
› Disease
|
|---|
| Graphical | 
|
|---|
| |
