Keyword
Hypusine biosynthesis
| Definition | Protein involved in the synthesis of hypusine, an amino acid formed by the two posttranslational steps in the modification of a lysine: (i) deoxyhypusine synthase catalyzes the transfer of a 4-aminobutyl moiety from spermidine to a specific lysine residue to form a deoxyhypusine residue, N-epsilon-(4-aminobutyl)lysine, and (ii) deoxyhypusine hydroxylase catalyzes the hydroxylation of the deoxyhypusine residue to form hypusine (N-epsilon-(4-amino-2-hydroxybutyl)lysine). |
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| Synonyms |
Hypusine synthesis
Hypusine anabolism
Hypusine biosynthetic process
Hypusine formation
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| Category |
› Biological process
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| GO | › peptidyl-lysine modification to hypusine [ GO:0008612 ]
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| Graphical | 
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