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Keyword - DNA-directed RNA polymerase (KW-0240)

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Protein of the DNA-directed RNA polymerase complexes, which catalyze RNA synthesis the by addition of ribonucleotide units to a RNA chain using DNA as a template. They can initiate a chain de novo. Prokaryotes have a single enzyme for the three RNA types that is subject to stringent regulatory mechanisms. Eukaryotes have type I that synthesizes all rRNA except the 5S component, type II that synthesizes mRNA and hnRNA and type III that synthesizes tRNA and the 5S component of rRNA.


Cellular component


DNA-directed 5'-3' RNA polymerase activity [ GO:0003899 ]


DNA-directed RNA polymeraseTranscriptionCellular componentBiological process