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Keyword - DNA-binding (KW-0238)

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Protein which binds to DNA, typically to pack or modify the DNA, or to regulate gene expression. Among those proteins that recognize specific DNA sequences, there are a number of characteristic conserved motifs believed to be essential for specificity. Many DNA-binding domains are described in PROSITE.


Molecular function


DNA binding [ GO:0003677 ]


Molecular functionDNA-binding
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