Keyword Dental caries
Protein involved in dental caries or important in the prevention of dental caries. Dental caries are localized destruction of the tooth surface, initiated by decalcification of the enamel and followed by enzymatic lysis of organic structures, the result of which is cavity formation. The cavity may penetrate the enamel and dentin, and reach the pulp. The disease may be caused by acids produced by bacteria which lead to decalcification, or by microorganisms that destroy the enamel protein, or by keratolytic microorganisms producing chelates that lead to decalcification.