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Keyword - Coenzyme A biosynthesis (KW-0173)

Definition

Protein involved in the biosynthetic pathway leading from pantothenate to coenzyme A (CoA). CoA has two halves in phosphodiester linkage: a 3',5'-ADP residue, and 4-phosphopantetheine. The phosphopantetheine moiety is itself composed of three structural entities: a branched chain dihydroxy acid in amide linkage to a beta-alanyl residue, which is in turn linked to a cysteamide containing the reactive thiol. Coenzyme A functions as a carrier of acetyl and acyl groups and is essential for numerous biosynthetic, energy-yielding, and degradative metabolic pathways. Acetyl-CoA is the common cellular currency for acetyl transfers.

Synonyms

  • CoA anabolism
  • CoA biosynthesis
  • CoA biosynthetic process
  • CoA formation
  • CoASH anabolism
  • CoASH biosynthesis
  • CoASH biosynthetic process
  • CoASH formation
  • CoASH synthesis
  • CoA synthesis
  • Coenzyme A anabolism
  • Coenzyme A biosynthetic process
  • Coenzyme A formation
  • Coenzyme A synthesis

Category

Biological process

GOi

coenzyme A biosynthetic process [ GO:0015937 ]

Graphical

Coenzyme A biosynthesisBiological process

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