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Keyword - Amyloid (KW-0034)

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Prion

Definition

Proteins which may form wide, insoluble, unbranched filaments possessing a cross-beta sheet quaternary structure, where the beta sheets are oriented perpendicular to the fibre axis. Amyloid fibrils may be involved in abnormal protein depositions, or amyloidosis, such as Alzheimer's or Parkinson's diseases. Functional amyloids, found in a wide range of organism, from bacteria to mammals are involved in diverse functions such as biofilm formation, formation of aerial hyphae, long-term memory or regulation of melanin biosynthesis.

Synonyms

  • Amyloid fibre-forming
  • Amyloid fibril-forming
  • Amyloid filament-forming
  • Amyloid-forming
  • Amyloid-like fibre-forming
  • Amyloid-like fibril-forming
  • Amyloid-like filament-forming
  • Functional amyloid

Category

Cellular component

Graphical

AmyloidCellular component